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Research Article

Antenatal anxiety symptoms outperform antenatal depression symptoms and suicidal ideation as a risk factor for postpartum suicidal ideation

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Received 24 Nov 2022, Accepted 16 Mar 2024, Published online: 25 Mar 2024
 

ABSTRACT

Background and Objectives

Suicidal ideation (SI) during the postpartum phase is linked with suicide, a leading cause of death during this period. Antenatal depression and anxiety symptoms have both been linked with increased risk for postpartum SI. However, research aimed at examining the relative contributions of antenatal anxiety and depression symptoms towards postpartum SI remains nascent. In this study, we investigated the relative contribution of antenatal anxiety symptoms, depression symptoms, and SI towards postpartum SI.

Design

These data are from a longitudinal study in which American mothers were assessed during pregnancy and again at six- to eight weeks postpartum.

Methods

Data were analyzed using correlations and logistic regression models.

Results

Antenatal anxiety symptoms and antenatal depression symptoms were significantly correlated with postpartum SI. Results from a logistic regression model indicated that antenatal anxiety symptoms (T1; OR = 1.185 [1.125, 1.245], p = .004), but not antenatal depression symptoms (T1; OR = 1.018 [0.943, 1.093], p = .812) or antenatal SI (T1; OR = 1.58 [0.11, 22.29], p = 0.73), were significantly associated with postpartum SI.

Conclusions

Antenatal anxiety symptoms, depression symptoms, and SI were positively associated with postpartum SI. When examined simultaneously, anxiety symptoms during the antenatal phase (but not depression symptoms or SI) predicted SI in the postpartum phase.

Acknowledgments

We would like to thank Bill Hambsh, David O’Bryan, Erin Ryals, and the staff at North Florida Women’s Care for their support with subject recruitment.

Data sharing

Data are available upon request from Liz Mulligan, PhD [email protected].

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by the following grants: National Institutes of Mental Health [grant number R21MH116481], National Institutes of Mental Health [grant number F31MH125624], Department of Defense [grant number W81XWH-16-2-0003], VA 3Q072019C

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